Epithalon is a synthetic tetrapeptide that produces the same effect as epithalamin, a natural polypeptide produced by pineal gland
In my own clinical practice, I already recommend a full blood count as part of annual review, to ensure that the person is not anaemic and, thus, that the HbA 1c is reliable, but this also proves useful to assess MCV in this context
It fits at the base of the toilet and elevates the feet, putting us into a squat position, which has been shown to straighten the colorectal canal and decrease the need to strain with a bowel movement
In one mouse study, researchers found that the peptide reduced the pain felt by the animals in their paws when placed on a mildly hot plate. The authors explained that this could be because GHK is similar in structure to cimetidine, a histamine H2 receptor antagonist sometimes given to reduce pain in certain digestive conditions.3 10 In rodents, doses as low as 0.5mg/kg were found to be effective in delivering these anti-pain effects.25 In a 70kg human, an equivalent dose would be around 5.6mg, though thats likely higher than necessary: pharmaceutical-grade GHK-Cu normally ranges from 0.5 mg to 2.5mg per injection
Kidney function was evaluated using the urea assay kit (Beyotime, S0574) and the Amplex Red creatinine assay kit (Beyotime, S0291)
